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艾塞那肽 Exenatide 141732-76-5多肽原料研发生产西林瓶EP管包装发货

更新时间:2024-11-13 08:00:00
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详细介绍
中文名醋酸艾塞那肽
英文名Exenatide acetate
别名依克那肽
醋酸恩夫韦地
乙酸艾塞那肽
醋酸艾塞那肽
艾塞那肽杂质
艾塞那肽醋酸盐
醋酸艾塞那肽 141732-76-5
醋酸艾塞那肽 EXENATIDEACETATE
英文别名Exenatide
Extendin-4
ExenatideAcetate
Exenatide acetate
EXENATIDE ACETATE
Exenatide Acettate
ENFUVIRTIDE ACETATE
enfuvirtide acetate
EXENATIDE ACETATE(EXENDIN-4)
His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH{2}
His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
CAS141732-76-5
EINECS1592732-453-0
化学式C186H286N50O62S
分子量4244.60796
熔点>209°C (dec.)
溶解度乙腈 (微溶),水 (微溶)
存储条件Refrigerator, under inert atmosphere
外观固体
颜色White to Off-White
物化性质白色粉末,可溶于甲醇、乙醇、DMSO等有机溶剂。
体外研究A cell-cell fusion assay reveals that the effective concentration for achieving 50% inhibition (IC 50 ) of Enfuvirtide is 23 ± 6 nM. IFN-λs (1, 2, or 3) or the antiretrovirals (AZT, Efavirenz, Indinavir, and Enfuvirtide) significantly inhibita the expression of HIV p24 antigen and Gag gene in macrophages. IFN-λs (1, 2, or 3) also enhanced the anti-HIV (Bal) effect of AZT, Efavirenz, Indinavir, and Enfuvirtide.
体内研究Enfuvirtide has a T 1/2 of 3.8 h.

盐酸奈必洛尔原料-多肽GLP-1原料-睾酮激素甾体-南京辰瑞晟生物医药科技公司,

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