缬沙坦缬沙坦相关物A (R)-缬沙坦CAS: 137862-53-4原料供应发货仅供科研实验

更新时间：2024-11-23 08:00:00

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详细介绍

中文名	缬沙坦
英文名	Valsartan
别名	缬沙坦缬沙坦相关物A (R)-缬沙坦缬沙坦EP杂质A 缬沙坦相关物质A 盐酸氨溴索杂质D 缬沙坦(标准品) 缬沙坦相关化合物A 缬沙坦USP相关物质A 原研CGP 49309 缬沙坦(盐酸氨溴索杂质D) 缬沙坦溶液, 100PPM 缬沙坦, 一种非肽类血管紧张素II AT1受体拮抗剂 N-(1-戊酰基)-N-[4-[2-(1H-四氮唑-5-基)苯基]苄基]-L-缬氨酸 N-戊酰基-N-[[2'-(1H-四唑-5-基)[1,1'-联苯]-4-基]甲基]-D-缬氨酸 N-((2'-(1H-四唑-5-基)-[1,1'-联苯]-3-基)甲基)-N-戊酰基-L-缬氨酸 N-(1-氧代戊基)-N-[[2'-(1H-四氮唑-5-基)[1,1'-联苯]-3-基]甲基]-L-缬氨酸 (R)-2-(N-((2'-(1H-四唑-5-基)-[1,1'-联苯]-4-基)甲基)戊氨基)-3 - 甲基丁酸
英文别名	Valsartan ent-Valsartan VALSARTAN IMP C Valsartan(Diovan) Valsartan R-enantiomer Valsartan Related Compound A Ambroxol Hydrochloride Imp.D (R)-2-(N-((2'-(1H-tetrazol-5-yl) N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}valine (S)-N-Valeryl-N-([2'-(1H-tetrazole-5-yl)biphen-4-yl]methyl)valine N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine N-pentanoyl-N-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-D-valine N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-3-yl)methyl)-N-pentanoyl-L-valine N-(1-Oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]methyl]-L-valine N-(1-OXOPENTYL)-N-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-L-VALINE L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- L-VALINE,N-(1-OXOPENTYL)-N-[[2''-(1H-TETRAZOL-5-YL)[1,1''-BIPHENYL]-3-YL]METHYL]- (R)-2-[N-[[2'-(5-Tetrazolyl)-4-biphenylyl]methyl]pentanamido]-3-methylbutanoic Acid D-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI) L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]methyl]- (9CI) 3-Methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic aci 3-methyl-2-[pentanoyl-[[4-[2-(2h-tetrazol-5-yl)phenyl]phenyl]methyl]amino]-butanoic acid (S)-2-(N-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic aci (R)-2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoic acid (S)-N-(1-carboxy-2-methyl-prop-1-yl)-N-pentanoyl-N-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]amine
CAS	137862-53-4 137863-60-6 137862-87-4
EINECS	1592732-453-0
化学式	C24H29N5O3
分子量	435.52
InChI	InChI=1/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m1/s1
InChIKey	ACWBQPMHZXGDFX-QFIPXVFZSA-N
密度	1.212±0.06 g/cm3(Predicted)
熔点	116-117°C
沸点	684.9±65.0 °C(Predicted)
闪点	368°C
水溶性	84.99mg/L(25 ºC)
蒸汽压	1.06E-19mmHg at 25°C
溶解度	DMSO: ≥ 20 mg/mL
折射率	1.586
酸度系数	3.56±0.10(Predicted)
存储条件	2-8°C
稳定性	吸湿性
敏感性	Easily absorbing moisture
外观	粉末
颜色	white to tan
Merck	14,9916
物化性质	从二异丙醚结晶，熔点116--117℃。
MDL号	MFCD00865840
体外研究	Valsartan剂量依赖性抑制血管紧张素II诱导的血管收缩，降低高血压的肾素依赖性模型的血压。Valsartan是至少一样有效的ACE抑制剂，利尿剂，β-阻断剂和钙拮抗剂。