盐酸阿霉素CAS: 25316-40-9原料供应仅供科研实验或出口

更新时间：2024-11-23 08:00:00

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详细介绍

中文名	盐酸阿霉素
英文名	doxorubicin hydrochloride
别名	盐酸阿霉素盐酸多柔吡星盐酸柔红霉素盐酸多柔比星阿霉素 (盐酸阿霉素) 盐酸阿霉素, 一种抗菌剂 (8S-cis)-10-[(3-氨基-2,3,6-三去氧-a-L-来苏己吡喃基)-氧]-7,8,9,10-四氢-6,8,11-三羟基-8-羟基乙酰基-1-甲氧基-5,12-并四苯二酮盐酸盐 (8S-cis)-10-((3-氨基-2,3,6-三去氧-a-L-来苏己吡喃基)-氧)-7,8,9,10-四氢-6,8,11-三羟基-8-羟基乙酰基-1-甲氧基-5,12-并四苯二酮盐酸盐 (8S,10S)-1-甲氧基-6,8,11-三羟基-8-(2-羟基乙酰基)-10-[[(2R,4S,5S,6S)-4-氨基-5-羟基-6-甲基-2-四氢吡喃基]氧基]-7,8,9,10-四氢并四苯-5,12-二酮盐酸盐
英文别名	ADRIACIN ADRIBLASTINA ADRIAMYCIN HCL Doxorubicin HCL Doxorubicin, HCl ADRIAMYCIN HYDROCHLORIDE 14-HYDROXYDAUNOMYCIN HCL doxorubicin hydrochloride ADRIBLASTINA HYDROCHLORIDE 14-HYDROXYDAUNOMYCIN HYDROCHLORIDE (8s-cis)-10-((3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride (8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride
CAS	25316-40-9
EINECS	246-818-3
化学式	C27H30ClNO11
分子量	579.98
InChI	InChI=1/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
InChIKey	MWWSFMDVAYGXBV-RUELKSSGSA-N
熔点	216°C (dec.)(lit.)
沸点	810.3°C at 760 mmHg
比旋光度	D20 +248±2° (c = 0.1 in methanol)
闪点	443.8°C
水溶性	Soluble in water.
蒸汽压	9.64E-28mmHg at 25°C
溶解度	Soluble in DMSO at 100 mg/ml; very poorly soluble in ethanol; soluble in water at 10 mg/ml with slight warming.
酸度系数	pKa 8.25±0.60 (Uncertain);8.43±0.70 (Uncertain);11.9±0.4 (Uncertain);12.95±0.1 (Uncertain);13.8±0.70
存储条件	2-8°C
稳定性	Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months.
外观	solid
颜色	orange to dark red
Zui大波长(λmax)	['497nm(H2O)(lit.)']
Merck	14,3439
BRN	4229251
物化性质	盐酸盐为桔红色针状结晶，熔点204-205℃。溶于水和醇，不溶于丙酮、苯、氯仿、yimi。