双羟萘酸噻嘧啶CAS: 22204-24-6原料供应发货可接受预订单

更新时间：2025-01-30 08:00:00

价格：请来电询价

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型号:CMO

产地:国产

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详细介绍

中文名	双羟萘酸噻嘧啶
英文名	pyrantel pamoate sigmaultra
别名	抗虫灵恩波酸噻嘧啶双羟萘酸喹嘧啶双羟萘酸噻嘧啶双羟萘酸噻嘧啶标准品双羟萘酸噻嘧啶(噻嘧啶) 含 4,4′-亚甲基双(3-羟基-2-萘甲酸) 的 1-甲基-2-(2-[2-噻吩基]乙烯基)-1,4,5,6-四氢嘧啶化合物
英文别名	helmex NeMocid Piranver cobantril HelMintox antiminth Early Bird combantrin lombriareu Dog Wormer trilombrin cp-10423-16 pyrantel pamoate pirantel pamoate pyrantel embonate Pyrantel paMoate bioxtra pyrantel pamoate sigmaultra 2-naphthoicacid,4,4'-methylenebis(3-hydroxy-,compd.with(e)-1,4,5,6-tetrahy 1,4,5,6-tetrahydro-1-methyl-2-((E)-2-(2-thienyl)vinyl)pyrimidine 4,4'-methylenebis(3-hydroxy-2-naphthoate) 1,4,5,6-Tetrahydro-1-Methyl-2-[(1E)-2-(2-thienyl)ethenyl]pyriMidine 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylate] 4,4'-Methylenebis[3-hydroxy-2-naphthalenecarboxylic Acid coMpound with 1,4,5,6-Tetrahydro-1-Methyl-2-[(1E)-2-(2-thienyl)ethenyl]pyriMidine Pyrantel pamoate,1-Methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4′-methylenebis(3-hydroxy-2-naphthoic acid)
CAS	22204-24-6
EINECS	244-837-1
化学式	C34H30N2O6S
分子量	594.68
InChI	InChI=1/C23H16O6.C11H14N2S/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10/h1-10,24-25H,11H2,(H,26,27)(H,28,29);2,4-6,9H,3,7-8H2,1H3
熔点	266-267°C
沸点	642.7°C at 760 mmHg
闪点	356.5°C
蒸汽压	2.13E-17mmHg at 25°C
溶解度	Pratically insoluble in water, soluble in dimethyl sulfoxide, pratically insoluble in methanol.
存储条件	Sealed in dry,Room Temperature
外观	powder
颜色	yellow
BRN	9034755
物化性质	黄色至褐色晶体粉末
MDL号	MFCD00072037
体外研究	Pyrantel induces Ascaris suum muscle contraction, with a pEC 50 of 7.24. Pyrantel produces spastic paralysis of the nematode by selectively gating acetylcholine receptor ion-channels on nerve and muscle. Pyrantel (72 h) inhibits the survival of Ancylostoma ceylanicum , Necator americanus and Trichuris muris on the third-stage larvae (IC 50 s=90.9, 2.0, and 95.5 µg/mL, respectively) and adult worms (IC 50 s=>100, 7.6, and 34.1 µg/mL, respectively).
体内研究	Pyrantel (10 mg/kg; a single p.o.) reduces the worms in A. ceylanicum -infected hamsters, with the worm burden reduction of 87.2% and worm expulsion rate of 63.4%.