托萘酯(tolnaftate) CAS: 2398-96-1原料供应发货可接受预订单

更新时间：2025-01-18 08:00:00

价格：请来电询价

品牌:CRS

型号:CMO

产地:国产

联系电话：0571-87428035

联系手机： 15360676961

联系人：Allen

让卖家联系我

详细介绍

中文名	N-甲基-N-(3-间甲苯基)硫代氨基甲酸-2-萘酯
英文名	tolnaftate
别名	托萘酯托萘酯原料托萘酸盐杂质托萘酯(标准品) 托萘酯 USP标准品托萘酯系统适应性 EP标准品 N-甲基-N-(3-甲基苯基)硫代氨基甲酸-2-萘酯 N-甲基-N-(3-间甲苯基)硫代氨基甲酸-2-萘酯
英文别名	Aftate TOLAFTATE tolnaftate Chinofungin O-2-naphthyl N,3-dimethyl(thiocarbanilate) 2-naphthyl n-methyl-n-(3-tolyl)thionocarbamate O-naphthalen-2-yl methyl(3-methylphenyl)carbamothioate Carbanilic acid, m,N-dimethylthio-, O-2-naphthyl ester Carbanilic acid, N,m-dimethylthio-, O-2-naphthyl ester METHYL 3-TOLYLTHIOCARBAMIC ACID O-NAPHTHALEN-2-YL ESTER O-Naphthalen-2-yl N-methyl-N-(3-methylphenyl)thiocarbamate METHYL-[3-METHYLPHENYL]-CARBAMOTHIOIC ACID O-2-NAPHTHYL ESTER Carbamothioic acid, methyl(3-methylphenyl)-, O-2-naphthalenyl ester
CAS	2398-96-1
EINECS	219-266-6
化学式	C19H17NOS
分子量	307.41
InChI	InChI=1/C19H17NOS/c1-14-6-5-9-17(12-14)20(2)19(22)21-18-11-10-15-7-3-4-8-16(15)13-18/h3-13H,1-2H3
InChIKey	FUSNMLFNXJSCDI-UHFFFAOYSA-N
密度	1.1328 (rough estimate)
熔点	110.5-111.5°C
沸点	453.4±38.0 °C(Predicted)
闪点	228°C
水溶性	<0.1 g/100 mL at 22 ºC
蒸汽压	2.08E-08mmHg at 25°C
溶解度	Soluble in chloroform at 50 mg/ml. Sparingly soluble in ethanol or methanol
折射率	1.6970 (estimate)
酸度系数	-0.35±0.50(Predicted)
存储条件	Sealed in dry,2-8°C
敏感性	Sensitive to heat
外观	powder
颜色	white to off-white
*大波长(λmax)	['258nm(MeOH)(lit.)']
Merck	14,9519
MDL号	MFCD00056611
体外研究	Tolnaftate (NP-27) blocked sterol biosynthesis in fungal cells and cell extracts, with accumulation of squalene. This point of action was confirmed by the direct inhibition of microsomal squalene epoxidase from Candida albicans. Tolnaftate (NP-27) inhibited sterol biosynthesis, At 100 microM, tolnaftate caused up to a 30% release of intracellular [14C]aminoisobutyric acid.