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盐酸奥替尼啶 CAS: 70775-75-6原料供应发货南京工厂直销

更新时间:2024-12-01 08:00:00
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详细介绍
中文名盐酸奥替尼啶
英文名N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride
别名奥替尼啶杂质
盐酸奥替尼啶
奥替尼啶盐酸盐
奥克太啶盐酸盐
奥替尼定盐酸盐
奥替尼啶,奥克太啶
奥替尼啶 二盐酸盐
奥替尼啶 奥克太啶(双盐酸盐)
英文别名Octenidine HCl
Octenidine hydrochloride
ocenidine dihydrochloride
OCTENIDINE DIHYDROCHLORIDE
N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylaMMoniuM) dichloride
N,N'-(decane-1,10-diyldipyridin-1-yl-4-ylidene)dioctan-1-amine dihydrochloride
N,N'-(decane-1,10-diyldi-1(4H)-pyridyl-4-ylidene)bis(octylammonium) dichloride
N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis-1-octanaMine Hydrochloride
N,N'-(1,10-Decanediyldi-1(4H)-pyridinyl-4-ylidene)bis(1-octanamine) dihydrochloride
CAS70775-75-6
EINECS274-861-8
化学式C36H64Cl2N4
分子量623.82616
InChIInChI=1/C36H62N4.2ClH/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2;;/h23-26,31-34H,3-22,27-30H2,1-2H3;2*1H
InChIKeySMGTYJPMKXNQFY-UHFFFAOYSA-N
密度1.046[at 20℃]
熔点215-217℃
沸点609.3°C at 760 mmHg
闪点322.3°C
水溶性14.2g/L at 20℃
蒸汽压0Pa at 25℃
溶解度Soluble in dimethyl sulfoxide and methanol.
存储条件Keep in dark place,Inert atmosphere,Room temperature
稳定性Hygroscopic
外观Solid
颜色White to Off-White
Merck14,6754
体外研究Octenidine concentrations of less than1.5 μM (0.94 μg/mL) causes a greater than 99% reduction of tested microbial population within 15 min. Staphylococcus epidermidis is the most susceptible of the test organisms, and E. coli and C. albicans are the least susceptible.
体内研究The antimicrobial activity of octenidine hydrochloride (OCT) is maintained when applied to the skin of the hands and feet of cynomolgus monkeys. Aqueous octenidine, at a concentration of 0.2 to 1.6% reduces resident microflora populations from 90 to 99.98%. A significant reduction in plaque score is observed on the buccal tooth surfaces after daily topical application of 1% solutions of octenidine and chlorhexidine for 7 d; octenidine is more effective than chlorhexidine.


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