米铂CAS: 141977-79-9原料供应发货实验室仅供科研
更新时间：2024-11-27 08:00:00
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详细介绍
| 中文名 | 米铂 |
| 英文名 | (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II) |
| 别名 | 米铂 顺式-[双十四烷酸-(1R,2R)-1,2-环己二胺合铂(Ⅱ)]单水合物 顺[((1R,2R)-1,2-环己二胺-N,N')二(十四烷酰氧基)]合铂 |
| 英文别名 | DACHPM Miripla SM-11355 SM 11355 SMP-11355 Miriplatin DACHPt(II)(Myr)2 [(1R,2R)-1,2-Cyclohexanediamine]bis(myristato)platinum (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis... (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum (SP-4-2)-[(1R,2R)-1,2-Cyclohexanediamine-kappaN,kappaN'])bis(myristato-kappaO)platinum(II) |
| CAS | 141977-79-9 |
| 化学式 | C34H66N2O4Pt |
| 分子量 | 762 |
| 溶解度 | 10 mM in DMSO |
| 存储条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| 体外研究 | Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis. |
| 体内研究 | Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells. |
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