枸橼酸托法替尼 托法替尼杂质43CAS: 540737-29-9原料药研发供应中间体
| 中文名 | 枸橼酸托法替尼 |
| 英文名 | 1-Piperidinepropanenitrile, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, (3R,4R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) |
| 别名 | 枸橼酸托法替尼 托法替尼杂质43 枸橼酸 托法替尼-13C-D3 (3R,4R)-托法替尼柠檬酸盐 TOFACITINIB CITRATE枸橼酸托法替尼 3-((3R,4R)-4-甲基-3-(甲基(7H-吡咯并[2,3-D]嘧啶-4-基)氨基)哌啶-1-基)-3-氧代丙腈枸橼酸盐 3-[(3R,4R)-4-甲基-3-[甲基(7H-吡咯并[2,3-D]嘧啶-4-基)氨基]-1-哌啶基]-3-氧代丙腈-2-羟基丙烷-1,2,3-三甲酸盐 |
| 英文别名 | Xeljanz CP 690550-10 CP 690500-10 Tofacitinib citrate CP-690550 (Tofacitinib citrate) 1-Piperidinepropanenitrile, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-, (3R,4R)-, citrate (3R,4R)-1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine 2-hydroxy-1,2,3-propanetricarboxylate (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidinepropanenitrile 2-Hydroxy-1,2,3-propanetricarboxylate |
| CAS | 540737-29-9 |
| EINECS | 638-826-4 |
| 化学式 | C16H20N6O.C6H8O7 |
| 分子量 | 504.497 |
| InChI | InChI=1S/C16H20N6O.C6H8O7/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16;7-3(8)1-6(13,5(11)12)2-4(9)10/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t11-,13+;/m1./s1 |
| InChIKey | SYIKUFDOYJFGBQ-YLAFAASESA-N |
| 熔点 | 201 °C (decomp) |
| 溶解度 | DMSO: soluble5mg/mL (clear solution; warmed) |
| 存储条件 | room temp |
| 外观 | powder |
| 颜色 | white to beige |
| MDL号 | MFCD11616529 |
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