阿毗沙班 阿派沙班 阿哌沙班CAS: 503612-47-3原料药研发供应中间体
| 中文名 | 阿哌沙班 |
| 英文名 | 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide |
| 别名 | 阿毗沙班 阿派沙班 阿哌沙班 阿哌沙班对照品 阿派沙班 ?达马莫德 FACTOR XA抑制剂(APIXABAN) 4,5,6,7-四氢-1-(4-甲氧基苯基)-7-氧代-6-[4-(2-氧代-1-哌啶基)苯基]-1 4,5,6,7-四氢-1-(4-甲氧基苯基)-7-氧代-6-[4-(2-氧代-1-哌啶基)苯基]-1H-唑唑并[3,4-C]吡啶-3-羰胺 1-(4-甲氧基苯基)-7-氧代-6-[4-(2-氧代哌啶-1-基)苯基]-4,5,6,7-四氢-1H-吡唑[3,4-C]吡啶-3-甲酰胺 4,5,6,7-四氢-1-(4-甲氧基苯基)-7-氧代-6-[4-(2-氧代-1-哌啶基)苯基]-1H-吡唑并[3,4-C]吡啶-3-甲酰胺 |
| 英文别名 | Apixaban BMS562247 BMS-562247 BMS 562247-01 BMS-562247-01 Apixaban, BMS 562247-01 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxaMide 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide 1H-Pyrazolo[3,4-c]pyridine-3-carboxamide, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]- 1-(4-Methoxy-phenyl)-7-oxo-6-[4-(2-oxo-piperidin-1-yl)-phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid aMide |
| CAS | 503612-47-3 |
| EINECS | 639-684-6 |
| 化学式 | C25H25N5O4 |
| 分子量 | 459.5 |
| InChI | InChI=1/C25H25N5O4/c1-34-19-11-9-18(10-12-19)30-23-20(22(27-30)24(26)32)13-15-29(25(23)33)17-7-5-16(6-8-17)28-14-3-2-4-21(28)31/h5-12H,2-4,13-15H2,1H3,(H2,26,32) |
| 密度 | 1.42 |
| 熔点 | 235-238°C |
| 沸点 | 770.5±60.0 °C(Predicted) |
| 闪点 | 419.764°C |
| 蒸汽压 | 0mmHg at 25°C |
| 溶解度 | DMSO (Slightly, Heated), Methanol (Slightly) |
| 折射率 | 1.705 |
| 酸度系数 | 15.01±0.20(Predicted) |
| 存储条件 | Refrigerator |
| 外观 | Solid |
| 颜色 | White to Off-White |
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