Degarelix 地加瑞克 214766-78-6原料供应仅供科研 冻干工艺 可发货
| 中文名 | 醋酸地加瑞克 |
| 英文名 | D-Alaninamide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-ly |
| 别名 | 地加瑞克 醋酸地加瑞克 地加瑞克-D7 地加瑞克醋酸盐 DEGARELIX游离 |
| 英文别名 | FirMagon Firmagon Degarelix DEGARELIX Degarelix acetate Degarelix acetate salt Degarelix, Degarelix acetate Degarelix acetate(FE-200486,Degarelix) N-Acetyl-3-(2-naphthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-4-[2,6-dioxohexahydropyrimidin-4(S)-ylcarboxamido]-L-phenylalanyl-4-ureido-D-phenylalanyl-L-leucyl-N6-isopropyl-L-lysyl-L-prolyl-D-alaninamide acetate D-Alaninamide,N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyrimidinyl]carbonyl]amino]-L-phenylalanyl-4-[(aminocarbonyl)amino]-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-ly D-Alaninamide, N-acetyl-3-(naphtalen-2-yl)-D-alanyl-4-chloro-D-phenylalanyl-3-(pyridin-3-yl)-D-alanyl-L-seryl-4-((((4S)-2,6-dioxohexahydropyrimidin-4-yl)carbonyl)amino)-L-phenylalanyl-4-(carbamoylamino)-D-phenylalanyl-L-leucyl-N6-(1-methylethyl)-L-lysyl-L-prolyl- |
| CAS | 214766-78-6 |
| EINECS | 807-277-4 |
| 化学式 | C82H103ClN18O16 |
| 分子量 | 1632.26 |
| 密度 | 1.325±0.06 g/cm3(Predicted) |
| 酸度系数 | 10.38±0.40(Predicted) |
| 存储条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| 体外研究 | Degarelix acts directly on the pituitary receptors for luteinizing hormone-releasing hormone (LHRH), blocking the action of endogenous LHRH. The use of degarelix eliminates the initial undesirable surge in gonadotropin and testosterone levels, which is produced by agonists of LHRH. Degarelix treatment reduces cell viability in all prostate cell lines (WPE1-NA22, WPMY-1, BPH-1 cells, VCaP cells), with the exception of the PC-3 cells. The GnRH antagonist degarelix exerts a direct effect on prostate cell growth through apoptosis. |
盐酸奈必洛尔原料-多肽GLP-1原料-睾酮激素甾体-南京辰瑞晟生物医药科技公司，
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