特利加压素 Terlipressin 14636-12-5多肽原料研发生产西林瓶EP管包装发货
| 中文名 | 特利加压素 |
| 英文名 | Terlipressin |
| 别名 | 利加压素 特利加压素 酸特利加压素 醋酸胸腺肽AL 醋酸特利加压素 特利加压素-多肽原料委托生产 特利加压素-多肽制剂一致性评价 |
| 英文别名 | Terlipressin Nα-Gly-Gly-Gly-8-Lys-vasopressin 1-Triglycyl-8-lysine Vasopressin Nα-Glycylglycylglycyl-vasopressin [N-α-Triglycyl-8-lysine]-vasopressin Nα-Glycyl-glycyl-glycyl-lysine-vasopressin Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin n-(n-(n-glycylglycyl)glycyl)-8-l-lysinevasopressin Terlipressin, Terlipressine, Terlipressina, Terlipressinum (2s)-1-[(4s,7s,10s,13s,16s,19s)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-n-[(1s)-5-amino-1-(carbamoylmethylcarbamoyl)pentyl]pyrrolidine-2-carboxamide (2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide (non-preferred name) |
| CAS | 14636-12-5 |
| EINECS | 238-680-8 |
| 化学式 | C52H74N16O15S2 |
| 分子量 | 1227.37 |
| InChI | InChI=1/C52H74N16O15S2/c53-17-5-4-9-31(45(76)60-23-41(57)72)63-51(82)38-10-6-18-68(38)52(83)37-27-85-84-26-36(61-44(75)25-59-43(74)24-58-42(73)22-54)50(81)65-34(20-29-11-13-30(69)14-12-29)48(79)64-33(19-28-7-2-1-3-8-28)47(78)62-32(15-16-39(55)70)46(77)66-35(21-40(56)71)49(80)67-37/h1-3,7-8,11-14,31-38,69H,4-6,9-10,15-27,53-54H2,(H2,55,70)(H2,56,71)(H2,57,72)(H,58,73)(H,59,74)(H,60,76)(H,61,75)(H,62,78)(H,63,82)(H,64,79)(H,65,81)(H,66,77)(H,67,80)/t31-,32-,33-,34-,35-,36-,37-,38-/m0/s1 |
| 密度 | 1.46±0.1 g/cm3(Predicted) |
| 熔点 | >170°C (dec.) |
| 沸点 | 1824.0±65.0 °C(Predicted) |
| 闪点 | 1056.9°C |
| 蒸汽压 | 0mmHg at 25°C |
| 溶解度 | DMSO (微溶) 、甲醇 (微溶) |
| 折射率 | 1.664 |
| 酸度系数 | 9.90±0.15(Predicted) |
| 存储条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| 外观 | 固体 |
| 颜色 | White |
| 体内研究 | Using a mouse nonlethal hepatic ischemia-reperfusion (IR) model, Terlipressin administration significantly ameliorates IR-induced liver apoptosis, necrosis and inflammation. |
盐酸奈必洛尔原料-多肽GLP-1原料-睾酮激素甾体-南京辰瑞晟生物医药科技公司，
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