斯他夫定 司他夫啶 司他夫定CAS: 3056-17-5原料药供应发货
| 中文名 | 司他夫定 |
| 英文名 | Stavudine |
| 别名 | 斯他夫定 司他夫啶 司他夫定 司他呋啶 止血宝(新凝灵) 司他夫定3056-17-5 二乙酰氨基乙酸乙二胺(司他夫定) 3'-脱氧-2',3'-双脱氢胸甙 3'-脱氧-2',3'-双脱氢胸苷 D4T.司他夫定(STAVUDINE) 2′,3′-二脱氢-3′-脱氧胸苷, 核苷类似物,能抑制HIV逆转录酶 |
| 英文别名 | ZERIT Stavir STAVUDINE Stavudine NSC 163661 3'-deoxythymidin-2'-ene 3'-DEOXY-2',3'-DIDEHYDROTHYMIDINE 3'-deoxy-2',3'-didehydrothymidine 2',3'-didehydro-3'-deoxythymidine Thymidine, 2'', 3''-didehydro-3''-deoxy- STAVUDINE[2'',3''-DIDEHYDRO-3''-DEOXYTHYMIDINE] 1-[5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methyl-hexahydropyrimidine-2,4-dione 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione |
| CAS | 3056-17-5 |
| EINECS | 641-374-0 |
| 化学式 | C10H12N2O4 |
| 分子量 | 224.21 |
| InChI | InChI=1/C10H14N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-3,6-8,13H,4-5H2,1H3,(H,11,14,15) |
| InChIKey | XNKLLVCARDGLGL-JGVFFNPUSA-N |
| 密度 | 1.374±0.06 g/cm3(Predicted) |
| 熔点 | 159-160°C |
| 比旋光度 | D25 -39.4° (c = 0.701 in water); D20 -46.1° (c = 0.7 in water) |
| 水溶性 | 5-10 g/100 mL at 21 ºC |
| 溶解度 | Soluble in water, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride. It shows polymorphism (5.9). |
| 折射率 | -46 ° (C=0.69, H2O) |
| 酸度系数 | 9.47±0.10(Predicted) |
| 存储条件 | -20°C |
| 稳定性 | Stable. Combustible. Incompatible with strong oxidizing agents. |
| 外观 | neat |
| 颜色 | White |
| 物化性质 | 从乙醇-苯中得无色颗粒状固体，熔点165--166℃。也有报道从乙醇-yimi中得结晶，熔点174℃。UVZui大吸收(水)：266nm(ε10149)。[α]D20-46.1°(C=0.7，水)。也有报道[α]D23-39.4°(C=0.701，水)。 |
| MDL号 | MFCD00132921 |
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