倍他米松(Betamethasone) CAS: 378-44-9皮质激素原料供应厂家品质保障
| 中文名 | 倍他米松 |
| 英文名 | Betamethasone |
| 别名 | 贝他美松 β-美松 倍他美松 倍他米松 培他美松 倍他米松原料药 倍他米松(标准品) 倍他米松溶液, 100PPM BETAMETHASONE 倍他米松 16b-甲基-11b,17a,21-三羟基-9a-孕甾-1,4-二烯-3,20-二酮 |
| 英文别名 | Betamethasone 17,21-trihydr Betamethasone base Betamethasone (200 mg) BetaMethasone SolutioM betamethasone standard BetaMethasone (Celestone) 9alpha-fluoro-16beta-methylprednisolone 9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 9a-fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione (11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro- 11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl- 6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one Betamethasone,9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisolone |
| CAS | 378-44-9 |
| EINECS | 206-825-4 |
| 化学式 | C22H29FO5 |
| 分子量 | 392.47 |
| InChI | InChI=1/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 |
| 密度 | 1.1283 (estimate) |
| 熔点 | 235-237°C |
| 沸点 | 568.2±50.0 °C(Predicted) |
| 比旋光度 | D +108° (acetone) |
| 闪点 | 297.5°C |
| 水溶性 | 58mg/L(25 ºC) |
| 蒸汽压 | 2.81E-15mmHg at 25°C |
| 溶解度 | Practically insoluble in water, sparingly soluble in anhydrous ethanol, very slightly soluble in methylene chloride. |
| 折射率 | 118 ° (C=1, Dioxane) |
| 酸度系数 | 12.13±0.70(Predicted) |
| 存储条件 | 0-6°C |
| 外观 | neat |
| 颜色 | White to Off-White |
| Merck | 14,1180 |
| 物化性质 | 白色结晶性粉末。熔点231-234℃（分解）。无臭。醋酸倍他米松（[987-24-6]）亦为白色结晶性粉末，熔点205-208℃，微溶于丙醇、乙醇，极难溶于氯仿或yimi，不溶于水，无臭。 |
| 体外研究 | Betamethasone对II型糖皮质激素受体具有特异亲合力,存在于大多数脑区。 |
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