甲钴胺(Mecobalamin) CAS: 13422-55-4原料供应发货仅供科研
| 中文名 | 甲钴胺 |
| 英文名 | Mecobalamin |
| 别名 | 甲钴胺 甲基钴胺素 甲钴胺水合物 甲基维生素B VB(12)甲钴胺 甲钴胺VB12 原料粉 甲基钴胺素(-20℃) 甲钴胺VB12,COΑ-[Α-(5,6-二甲基苯并咪唑基)]-Β甲钴酰胺 |
| 英文别名 | Algobaz Mecobalamin MECOBALAMIN Vitamin B12 MECOBALAMINE Methylcobalamin METHYLCOBALAMIN Methyl Vitamin B12 cobalt-methylcobalamin Methyl-5,6-dimethylbenzimidazolylcobalamin cobinamide,cobalt-methylderivative,hydroxide,dihydrogenphosphate(ester), |
| CAS | 13422-55-4 |
| EINECS | 236-535-3 |
| 化学式 | C63H90CoN13O14P |
| 分子量 | 1343.4 |
| InChI | InChI=1/C62H90N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3;/q;-1;+3/p-2/t31?,34-,35-,36-,37+,41+,52?,53?,56?,57+,59-,60+,61+,62+;;/m1../s1 |
| InChIKey | JEWJRMKHSMTXPP-WYVZQNDMSA-L |
| 熔点 | >190°C (dec.) |
| 水溶性 | Partially soluble in cold water, hot water. |
| 溶解度 | DMSO (Slightly), Methanol (Sparingly), Water (Slightly) |
| 酸度系数 | pK1:7.64(+1) (25°C) |
| 存储条件 | Sealed in dry,Store in freezer, under -20°C |
| 稳定性 | Light Sensitie |
| 敏感性 | Sensitive to light |
| 外观 | Solid |
| 颜色 | Dark Red |
| 物化性质 | 本品为深红色晶体或结晶性粉末，易溶于水，微溶于乙醇，不溶于丙酮，见光不稳定 |
| MDL号 | MFCD00082483 |
| 体外研究 | Methylcobalamin (CH3-B12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyanide is replaced by a methyl group. Methylcobalamin (CH3-B12) features an octahedral cobalt(III) centre. Methylcobalamin (CH3-B12) can be obtained as bright red crystals. From the perspective of coordination chemistry, Methylcobalamin (CH3-B12) is notable as a rare example of a compound that contains metal-alkyl bonds. Methylcobalamin (CH3-B12) is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lack of vitamin B12 (vitamin B12 deficiency), such as pernicious anemia. Methylcobalamin (CH3-B12) is also used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis. From Wikipedia. |
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