叠氮胸苷 齐多夫定 叠氮脱氧胸苷CAS: 30516-87-1原料供应发货仅供科研试验
| 中文名 | 齐多夫定 |
| 英文名 | Zidovudine |
| 别名 | 叠氮胸苷 齐多夫定 叠氮脱氧胸苷 3'-叠氮脱氧胸苷 齐多夫定(标准品) 3'-叠氮-3'-脱氧胸苷 3'-叠氮-3'-脱氧胸甙 1-[4-迭氮基-5-(羟甲基)四氢呋喃-2-基]-5-甲基嘧啶-2,4(1H,3H)-二酮 1-(4-迭氮基-5-(羟甲基)四氢呋喃-2-基)-5-甲基嘧啶-2,4(1H,3H)-二酮 |
| 英文别名 | Zidovudine azidothymidine Zidovudine(AZT) Zidovudine solution 3'-Azido-3'-thymidine 3'-Deoxy-3'-azidothymi 3-Azido-3-deoxy-thymidine 3'-azido-3'-deoxythymidine 1-(3-Azido-2,3-Dideoxy-Beta-D-Ribofuranosyl)Thymine 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione 1-[4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione 1-(3-azido-2,3-dideoxypentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-[4-azido-5-(hydroxymethyl)-2-tetrahydrofuranyl]-5-methylpyrimidine-2,4-dione 1-[4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione 1-(4-azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1h-pyrimidine-2,4-dione 1-[4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione 1-(3-azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-[(3xi)-3-azido-2,3-dideoxy-beta-D-glycero-pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione |
| CAS | 30516-87-1 |
| EINECS | 623-849-4 |
| 化学式 | C10H13N5O5 |
| 分子量 | 283.24 |
| InChI | InChI=1/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8-/m0/s1 |
| InChIKey | HBOMLICNUCNMMY-BWZBUEFSSA-N |
| 密度 | 1.3382 (rough estimate) |
| 熔点 | 113-115 °C (lit.) |
| 沸点 | 410.43°C (rough estimate) |
| 比旋光度 | D25 +99° (c = 0.5 in water) |
| 闪点 | 9℃ |
| 水溶性 | 1-5 g/100 mL at 17 ºC |
| 溶解度 | H2O: 50mg/mL |
| 折射率 | 47 ° (C=1, H2O) |
| 酸度系数 | pKa 9.53(H2Ot = 25.0±0.1I = 0.00) (Uncertain) |
| 存储条件 | 2-8°C |
| 稳定性 | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| 敏感性 | Light Sensitive & Hygroscopic |
| 外观 | Powder |
| 颜色 | White to Off-white |
| Merck | 14,10123 |
| BRN | 3595791 |
| 物化性质 | 从石油醚中得针状结晶，无臭。遇光分解。易溶于乙醇。水中溶解度(25℃)：25mg/ml。熔点106～112℃(石油醚)；也有报道熔点120～122℃(水)。[α]D23+99°(C=0.5，水)。UVZui大吸收(水)：266．5nm(ε11650)。急性毒性LD50雄、雌小鼠，雄、雌大鼠(mg/kg)：3568，3062，3084，3683口服全部＞750皮下注射。 |
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