地素 土霉素 地霉素CAS: 79-57-2原料仅供出口或科研试验
| 中文名 | 土霉素碱 |
| 英文名 | Oxytetracycline |
| 别名 | 地素 土霉素 地霉素 氧四素 氧四環素 土霉素碱 氧四环素 地靈黴素 4-二甲氨基-1,4,4a,5,5a,6,11,12a-八氢-3,5,6,10,12,12a-六羟基-6-甲基-1,11-二氧代-并四苯-2-甲酰胺 |
| 英文别名 | OTC Base adamycin antibiotictm25 Oxytetracycline Oxytetracycline Base 5-hydroxy-tetracyclin 5-Hydroxytetracycline 6-beta,12a-alpha))--alph 12,12a-hexahydroxy-6-methyl-1,11-dioxo-10 6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,[4s-(4alpha,4aalpha,5alpha,5a 6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,(4s-(4-alpha,4a-alpha,5-alpha,5a 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,2-Naphthacenecarboxamide (4S,4aR,6S,12aS)-4-(dimethylamino)-3,5,6,10,12,12a-hexahydroxy-6-methyl-11-oxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide (2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione |
| CAS | 79-57-2 |
| EINECS | 201-212-8 |
| 化学式 | C22H24N2O9 |
| 分子量 | 460.43 |
| InChI | InChI=1/C22H26N2O8/c1-21(31)9-5-4-6-10(25)11(9)17(27)12-13(21)18(28)14-15(24(2)3)16(26)8(20(23)30)7-22(14,32)19(12)29/h4-6,13-15,18,25-26,28-29,31-32H,7H2,1-3H3,(H2,23,30)/t13?,14-,15+,18?,21-,22+/m1/s1 |
| InChIKey | IWVCMVBTMGNXQD-PXOLEDIWSA-N |
| 密度 | 1.6340 |
| 熔点 | 183 °C |
| 沸点 | 565.29°C (rough estimate) |
| 比旋光度 | -223 º (c=1 0.03N HCl) |
| 闪点 | 447.954°C |
| 水溶性 | 0.2 g/L |
| 蒸汽压 | 0mmHg at 25°C |
| 溶解度 | Sparingly soluble in aqueous solution at 0.6 mg/mL |
| 折射率 | 1.6500 (estimate) |
| 酸度系数 | pKa 3.27/7.32/9.11(H2O,t =25,I<)(Approximate) |
| 存储条件 | Keep in dark place,Inert atmosphere,Room temperature |
| 外观 | Crystalline Powder |
| 颜色 | Beige to light yellow |
| 物化性质 | 淡黄色结晶性粉末。熔点182-182℃（分解）。微溶于乙醇，极微溶于水。在空气中稳定，遇光颜色渐暗，在碱性溶液中易破坏。吸附在碳酸钙中的制剂为黄褐色干燥粉末。盐酸盐为黄色结晶粉末，无臭，味微苦。熔点190-194℃，在室温下长期保存不变质，不失效。易溶于水和甲醇，略溶于乙醇，不溶于氯仿、yimi。其水溶液在酸性条件下稳定，碱性条件下不稳定。 |
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