氯雷他定(Loratadine) CAS: 79794-75-5原料供应仅供科研实验或出口
| 中文名 | 氯雷他定 |
| 英文名 | Loratadine |
| 别名 | 克敏能 氯雷他丁 氯雷他定 氯雷他定D5 地氯雷他定EP杂质C 越桔天然红色素(花青素) LORATADINE 氯雷他定 4-(8-氯-5,6-二氢-11H-苯并[5,6]环庚基[1,2-b]并吡啶-11-烯)-1-哌啶羧酸乙脂 4-(8-氯-5,6-二氢-11H-苯并[5,6]环庚基[1,2-b]并吡啶-11-烯)-1-哌啶羧酸乙酯 |
| 英文别名 | CLARITIN CLARATYNE Loratidine Loratadine LORATIDINE LORATADINE LORATADINE-D5 ethyl 4-(8-chloro-5,6-dihydro-11h-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate 4-(8-Chloro-10,11-dihydro-4-aza-5H-dibenzo[a,d]cycloheptene-5-ylidene)piperidine-1-carboxylic acid ethyl ester 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine-11-ylidene)piperidine-1-carboxylic acid ethyl ester |
| CAS | 79794-75-5 |
| EINECS | 1308068-626-2 |
| 化学式 | C22H23ClN2O2 |
| 分子量 | 382.88 |
| InChI | InChI=1/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3 |
| InChIKey | JCCNYMKQOSZNPW-UHFFFAOYSA-N |
| 密度 | 1.261±0.06 g/cm3(Predicted) |
| 熔点 | 134-136°C |
| 沸点 | 531.3±50.0 °C(Predicted) |
| 水溶性 | It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol. |
| 溶解度 | DMSO: 26mg/mL, soluble |
| 酸度系数 | 4.27±0.20(Predicted) |
| 存储条件 | 2-8°C |
| 稳定性 | Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents. |
| 外观 | powder |
| 颜色 | white |
| Merck | 14,5578 |
| 物化性质 | 从乙腈结晶，熔点134-136℃。 |
| 产品用途 | 国家二类抗过敏新药，用于缓解季节性过敏性鼻炎的鼻部和非鼻部症状及缓解慢性荨麻疹 |
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