辛伐他汀 (Simvastatin) CAS: 79902-63-9原料供应发货可接受预订单
| 中文名 | 斯伐他汀 |
| 英文名 | Simvastatin |
| 别名 | 舒降脂 塞瓦停 辛伐他 新伐他汀 斯伐他丁 斯伐他汀 辛伐他丁 辛伐他汀 西伐斯汀 辛伐司他汀 辛伐他汀D6 (1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-六氢-3,7-二甲基-8-[2-[(2R,4R)-四氢-4-羟基-6-氧代-2H-吡喃-2- (1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-六氢-3,7-二甲基-8-[2-[(2R,4R)-四氢-4-羟基-6-氧代-2H-吡喃-2-基]乙基]-1-萘酚 2,2-二甲基丁酸酯 |
| 英文别名 | Lodaiès Simvastatin 7-beta,8-beta(2s*,4s*),8a-beta))-alph (1s-(1-alpha,3-dro-4-hydroxy-6-oxo-2h-pyran-2-yl)ethyl)-1-naphthalenyleste [8-[2-(4-Hydroxy-6-oxo-tetrahydropyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl]2,2-dimethylbutanoate [(1S,3R,7R,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-oxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoat [(3R,7S,8S)-8-[2-[(2R,4R)-4-hydroxy-6-oxo-tetrahydropyran-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl 2,2-dimethyl-butanoate 2,2-Dimethylbutanoic acid (1S)-1,2,3,7,8,8aα-hexahydro-3β,7α-dimethyl-8α-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]naphthalen-1β-yl ester Butanoic acid, 2,2-dimethyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro- 4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1-alpha,3-alpha,7- beta,8-beta(2S*,4S*),8a-beta)) |
| CAS | 79902-63-9 |
| EINECS | 616-751-8 |
| 化学式 | C25H38O5 |
| 分子量 | 418.57 |
| InChI | InChI=1/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21?,23?/m0/s1 |
| 密度 | 1.11±0.1 g/cm3(Predicted) |
| 熔点 | 127-132 °C (lit.) |
| 沸点 | 564.9±50.0 °C(Predicted) |
| 比旋光度 | D25 +292° (c = 0.5% in acetonitrile) |
| 闪点 | 184.8°C |
| 蒸汽压 | 4.12E-15mmHg at 25°C |
| 溶解度 | DMSO: ≥20mg/mL |
| 折射率 | 1.53 |
| 酸度系数 | 13.49±0.40(Predicted) |
| 存储条件 | 2-8°C |
| 稳定性 | Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months. |
| 敏感性 | Sensitive to humidity and air |
| 外观 | solid |
| 颜色 | white |
| Merck | 14,8539 |
| 物化性质 | 白色结晶性粉末，无臭。易溶于乙醇、丙酮或乙腈，较难溶于**，几不溶于水。熔点135～138℃。 |
| 产品用途 | 具有降低胆固醇、低密度脂蛋白胆固醇和极低密度脂蛋白胆固醇的作用 |
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