1,1,3-三溴丙酮CAS: 3475-39-6原料供应发货
| 中文名 | 1,1,3-三溴丙酮 |
| 英文名 | 1,1,3-tribromo acetone |
| 别名 | 三溴丙酮 1,1,1三溴丙酮 1,1,3-三溴丙酮 1,1,3-三溴丙烷-2-一 1,1,3-三溴丙酮(具备生产资质) 1,1,3-三溴丙酮,甲氨蝶呤中间体 |
| 英文别名 | JACS-3475-39-6 1,1,3-TribromoAceton 1,1,3-Tribromoacetone 1,1,3-tribromoacetone 1,1,3-tribromo acetone 1,1,3-Tribromopropan-2-one 1,1,3-tribromopropan-2-one 2-Propanone,1,1,3-tribromo- TIANFU-CHEM--1,1,3-Tribromoacetone |
| CAS | 3475-39-6 |
| 化学式 | C3H3Br3O |
| 分子量 | 294.77 |
| InChI | InChI=1/C3H3Br3O/c4-1-2(7)3(5)6/h3H,1H2 |
| 密度 | 2.561±0.06 g/cm3(Predicted) |
| 熔点 | 28-29 °C |
| 沸点 | 114-116 °C(Press: 14 Torr) |
| 闪点 | 115.1°C |
| 蒸汽压 | 0.00875mmHg at 25°C |
| 折射率 | 1.595 |
| 体内研究 | Methotrexate (Amethopterin) reduces thymus and spleen indices of mice. Methotrexate markedly decreases white blood cells, thymic and splenic lymphocytes at dose ≥5 mg/kg. However, there is a significant difference between the treatment plus control group and the model group (p<0.01). The combination of grape seed proanthocyanidins and Siberian ginseng eleutherosides obviously diminishes the effects of Methotrexate exposure on indices of thymus and spleens in mice. Methotrexate (MTX) (2 mg/kg; i.p.; once in a week for 5 weeks) is effective in Freund's complete adjuvant-induced arthritis. The combination of Methotrexate (1 mg/kg; i.p.; once in a week for 5 weeks) and Curcumin (30 mg/kg and 100 mg/kg, thrice a week for 5 weeks; i.p.) shows a significant anti-arthritic action and protection from hematological toxicity. |
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