南京辰瑞晟生物医药科技有限公司
司美格鲁肽 , 阿法诺肽 , 索玛鲁肽 , 他达那非 , 甾体激素原料
氧氟沙星(ofloxacin) CAS: 82419-36-1原料生产供应仅供企业出口

中文名氧氟沙星
英文名ofloxacin
别名奥复星
氟嗪酸
利复星
菲宁达
可乐必妥
氧氟沙星
左氟沙星
氧氟多沙
奥氟哌酸
左氧氟沙星
左旋氧氟沙星
9-氟-2,3-二氢-3-甲基-10-(4-佳绩-哌嗪基)7-氧代-7H-吡啶并(1,2,3-DL)-1,4-苯并嗪-6-羧酸
(S)-9-氟-2,3-二氢-3-甲基-10-(4-甲基-1-哌嗪基)-7-氧代-7H-吡啶并[1,2,3-de]-[1,4]苯并噁嗪-6-羧酸
(+|-)-9-氟-2,3-二氢-3-甲基-10-(4-甲基-1-哌嗪基)-7-氧代-7H-吡啶并[1,2,3-de]-[1,4]苯并噁嗪-6-羧酸
(±)-9-氟-2,3-二氢-3-甲基-10-(4-甲基-1-哌嗪基)-7-氧代-7H-吡啶并[1,2,3-DE]-[1,4]-苯并噁嗪-6-羧酸盐酸盐
(S)-(-)-9-氟-2,3-二氢-3-甲基-10-(4-甲基-1-哌嗪基)-7-氧代-7H-吡啶并(1,2,3-de)-(1,4)-苯并恶嗪-6-酸
英文别名oflx
OFLX
Floxin
floxin
Oxaldin
TARIVID
Levaquin
ofloxacin
OFLOXACIN
Ofloxacine
Ofloxacina
Ofloxacino
Ofloxacinum
Floxin Otic
Levofloxacin
(S)-Ofloxacin
(-)-Ofloxacin
Levofloxacino
AKOS NCG1-0050
Ofloxacin Otic
Levofloxacinum
(S)-(-)-Ofloxacin
Ofloxacin S-(-)-form
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
(+-)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (+-)-
(-)-(s)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7h-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
(-)-(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazin-yl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid
CAS82419-36-1
100986-85-4
83380-47-6
EINECS680-263-1
化学式C18H20FN3O4
分子量361.37
InChIInChI=1/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
密度1.2688 (estimate)
熔点270-2750C
沸点571.5±50.0 °C(Predicted)
闪点299.4°C
水溶性Soluble in acetic acid or water. Slightly soluble in methanol
蒸汽压6.7E-14mmHg at 25°C
溶解度1 M NaOH: soluble50mg/mL
折射率1.669
酸度系数5.19±0.40(Predicted)
存储条件Keep in dark place,Sealed in dry,Store in freezer, under -20°C
外观neat
颜色Colorless needles from ethanol
Zui大波长(λmax)['326nm(H2O)(lit.)']
Merck14,6771
物化性质从乙醇中得到无色针状结晶,无臭,味苦。易溶于冰醋酸,较易溶于氯仿难溶于甲醇、乙醇、丙酮、氯仿或水,不溶于乙酸乙酯。熔点250~257℃(分解)。急性毒性LD50雄、雌小鼠,雄、雌大鼠(rng/kg):5450,5290,3590,3750口服;208,233,273,276静脉注射;>10000,>10000,7070,9000皮下注射。
MDL号MFCD00865049


发布时间:2024-11-25
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