特利加压素(Terlipressin) CAS: 14636-12-5原料供应发货可接受预订单

发布时间：2024-05-11

中文名	特利加压素
英文名	Terlipressin
别名	利加压素特利加压素酸特利加压素醋酸胸腺肽AL 醋酸特利加压素特利加压素-多肽原料委托生产特利加压素-多肽制剂一致性评价
英文别名	Terlipressin Nα-Gly-Gly-Gly-8-Lys-vasopressin 1-Triglycyl-8-lysine Vasopressin Nα-Glycylglycylglycyl-vasopressin [N-α-Triglycyl-8-lysine]-vasopressin Nα-Glycyl-glycyl-glycyl-lysine-vasopressin Nα-Glycyl-glycyl-glycyl-[8-lysine]-vasopressin n-(n-(n-glycylglycyl)glycyl)-8-l-lysinevasopressin Terlipressin, Terlipressine, Terlipressina, Terlipressinum (2s)-1-[(4s,7s,10s,13s,16s,19s)-19-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]-13-benzyl-10-(2-carbamoylethyl)-7-(carbamoylmethyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-n-[(1s)-5-amino-1-(carbamoylmethylcarbamoyl)pentyl]pyrrolidine-2-carboxamide (2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide (non-preferred name)
CAS	14636-12-5
EINECS	238-680-8
化学式	C52H74N16O15S2
分子量	1227.37
InChI	InChI=1/C52H74N16O15S2/c53-17-5-4-9-31(45(76)60-23-41(57)72)63-51(82)38-10-6-18-68(38)52(83)37-27-85-84-26-36(61-44(75)25-59-43(74)24-58-42(73)22-54)50(81)65-34(20-29-11-13-30(69)14-12-29)48(79)64-33(19-28-7-2-1-3-8-28)47(78)62-32(15-16-39(55)70)46(77)66-35(21-40(56)71)49(80)67-37/h1-3,7-8,11-14,31-38,69H,4-6,9-10,15-27,53-54H2,(H2,55,70)(H2,56,71)(H2,57,72)(H,58,73)(H,59,74)(H,60,76)(H,61,75)(H,62,78)(H,63,82)(H,64,79)(H,65,81)(H,66,77)(H,67,80)/t31-,32-,33-,34-,35-,36-,37-,38-/m0/s1
密度	1.46±0.1 g/cm3(Predicted)
熔点	>170°C (dec.)
沸点	1824.0±65.0 °C(Predicted)
闪点	1056.9°C
蒸汽压	0mmHg at 25°C
溶解度	DMSO (Slightly), Methanol (Slightly)
折射率	1.664
酸度系数	9.90±0.15(Predicted)
存储条件	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
外观	Solid
颜色	White
体内研究	Using a mouse nonlethal hepatic ischemia-reperfusion (IR) model, Terlipressin administration significantly ameliorates IR-induced liver apoptosis, necrosis and inflammation.

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